姜顺军;杨新云;刘榕敏;余捷;
JIANG Shun-jun1,YANG Xin-yun1,LIU Min-rong2,YU Jie2(1.The First Affiliated Hospital of Guangzhou Medical University,Guangzhou,Guangdong 510120,China; 2.Clinical School of Guangzhou Medical University,Guangzhou,Guangdong 510120,China)

• 1:广州医学院第一附属医院
• 2:广州医学院临床医学院

摘要(Abstract)：

目的了解和分析本院药品不良反应(ADR)的发生情况,为临床合理用药提供参考。方法调查分析本院2005～2011年期间收集的共2 112份ADR报告,从ADR上报人员、类型、患者一般情况、给药途径、ADR涉及的药物种类、累及的器官/系统分类、临床表现等进行统计汇总。结果新的和严重的ADR共占总数的5.73%;男女比例接近,60 a以上中老年患者893例,占总数42.28%;静脉给药1 694例,占总数80.21%;引起ADR前3位的药物为左氧氟沙星、阿奇霉素、环丙沙星;ADR临床表现主要为皮肤及其附件损害。结论应加强ADR的重点监测、主动监测和前瞻性监测工作,尽可能减少ADR的发生。
Objective To study and analyze the occurrence of ADR in the hospital,and provide the reference for clinical rational drug application.Methods A total of 2 112 ADR reports from 2005 to 2011 were collected.The ADR reports were analyzed in respects of report people,type,patients' condition,route of administration,the drug classification involved organs/system and the clinical manifestation.Results Among the 2 112 ADR reports,the new and severe ADR accounts for 5.73%,the ratio of men is close to women.893 cases(42.28%) were over 60 yeas old,1 694 cases received intravenous administration(80.21%).The top 3 drugs caused ADR include levofloxacin,azithromycin,ciprofloxacin.Lesions of skin and its appendix were the main clinical manifestations.Conclusion Intensive,active and prospective supervision should be strengthened to reduce the occurrence of ADR.

关键词(KeyWords)： 药品不良反应;分析;监测
adverse drug reactions;analysis;monitoring

Abstract:

Keywords:

基金项目(Foundation):

作者(Authors): 姜顺军;杨新云;刘榕敏;余捷;
JIANG Shun-jun1,YANG Xin-yun1,LIU Min-rong2,YU Jie2(1.The First Affiliated Hospital of Guangzhou Medical University,Guangzhou,Guangdong 510120,China; 2.Clinical School of Guangzhou Medical University,Guangzhou,Guangdong 510120,China)

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