今日药学

2021, v.31(11) 861-864

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基于Granada-Ⅱ分类法评价我院老年患者ADR/ADE涉及的药物相关问题
Analysis on Drug-related Problems Involved in ADR/ADE for the Elderly Patients in Our Hospital Based on Granada-Ⅱ Classification

邱正国;杨小娟;康群招;李尚书;
QIU Zhengguo;YANG Xiaojuan;KANG Qunzhao;LI Shangshu;Department of Pharmacy,Shenzhen Yantian District People's Hospital;

摘要(Abstract):

目的对我院老年患者药品不良反应/事件(ADR/ADE)进行调查分析,探讨我院老年患者药物临床应用的药物相关问题(drug-relatedproblems, DRPs),为我院老年患者药物的临床合理应用提供依据。方法以我院2014年1月~2020年12月上报的151例老年患者药物相关ADR/ADE为研究对象,探讨其发生特点,同时采用Granada-Ⅱ分类法对老年患者药物使用的必要性、有效性、安全性进行评价研究。结果涉及DRPs具体问题分类有DRPs2、DRPs3、DRPs4、DRPs5、DRPs6分别为18例、2例、1例、121例和9例。结论应重视老年患者药物临床应用的DRPs,避免老年人发生ADR/ADE,促进老年患者用药安全。
OBJECTIVE To analyzed the adverse reactions/events(ADR/ADE),and the drug-related problems(DRPs) of the elderly patients in our hospital, for providing reference for the clinical rational application of the elderly patients. METHODS 151 ADR/ADE of the elderly patients in our hospital were collected from January 2014 to December 2020.Then the occurrence characteristics were discussed, and the clinical effectiveness, necessity, safety of drug use were evaluated using Granada-Ⅱ classification method. RESULTS The specific problems related to DRPs were classified into DRPs2(18 cases),DRPs3(2 cases),DRPs4(1 case),DRPs5(121 cases),and DRPs6(9 cases). CONCLUSION We should pay attention to the DRPs in drug use for the elderly patients, avoiding the occurrence of ADR/ADE,so as to promote the safety of medication for the elderly patients.

关键词(KeyWords): 老年患者;药物相关问题;药品不良反应/事件;Granada-Ⅱ分类法;合理用药;安全用药
elderly patients;drug-related problems;adverse drug reaction/events;Granada-Ⅱ classification;rational drug use;safe medication

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作者(Author): 邱正国;杨小娟;康群招;李尚书;
QIU Zhengguo;YANG Xiaojuan;KANG Qunzhao;LI Shangshu;Department of Pharmacy,Shenzhen Yantian District People's Hospital;

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