今日药学

2010, v.20(07) 40-43

[打印本页] [关闭]
本期目录(Current Issue) | 过刊浏览(Past Issue) | 高级检索(Advanced Search)

胸腺肽致不良反应87例文献分析
Adverse Drug Reactions Induced by Thymosin Injection:Literature Analysis of 87 Cases

曾英彤;李洵;李智辉;
ZENG Ying-tong,LI Xun,LI Zhi-hui(Department of Pharmacy,Guangdong General Hospital,Guangdong Academy of Medical Sciences;Guangzhou,Guangdong 510120,China)

摘要(Abstract):

目的探讨胸腺肽注射剂致不良反应的一般规律及特点,指导临床合理用药。方法通过检索2000~2009年国内公开发行的医药学期刊报道应用胸腺肽注射剂致不良反应案例,并进行统计分析。结果胸腺肽注射剂致ADR在各年龄组基本上没有差异,发生时间多集中在用药后30 min内,主要表现为变态反应,以过敏性休克为主。结论临床应严格控制胸腺肽的适应症,用药前询问过敏史,皮试,密切监护,减少不良反应的发生。
Objective To study the general pattern and characteristics of the adverse drug reactions(ADRs) induced by thymosin injections and to direct rational drug use.Methods ADRs induced by thymosin injections published in domestic medical journals from 2000~2009 were retrieved and analyzed statistically.Results ADRs induced by thymosin injection occurred mostly within 30 minutes after drug administration in patients of different ages.The main ADRs of thymosin were allergic reactions,the most common manifestation was anaphylactic shock.Conclusion The scope of application should be strictly controlled in clincal practice.The allergic history of the patients should be inquired and skin test should be done before drug administration.The patient shuold be cared tightly after administration so as to reduce the incidences of ADRs.

关键词(KeyWords): 胸腺肽;不良反应;文献分析
thymosin;adverse drug reaction(ADR);literature analysis

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 曾英彤;李洵;李智辉;
ZENG Ying-tong,LI Xun,LI Zhi-hui(Department of Pharmacy,Guangdong General Hospital,Guangdong Academy of Medical Sciences;Guangzhou,Guangdong 510120,China)

Email:

DOI:

参考文献(References):

扩展功能
本文信息
服务与反馈
本文关键词相关文章
本文作者相关文章
中国知网
分享