曹媛;邓蓉蓉;孙萍萍;
CAO Yuan;DENG Rongrong;SUN pingping;Pharmacy Departnent of The First Affiliated Hospital,Sun Yat-Sen University;

• 1:中山大学附属第一医院药学部

摘要(Abstract)：

目的促进辅助治疗药物的合理使用。方法分析我院2015年辅助治疗药物专项点评中发现的主要问题,并评价干预后的效果。结果最常见不合理使用的药物分别为香菇多糖注射液(100.00%)、脱氧核苷酸注射液(67.50%)和小牛脾提取物注射液(60.00%);1 200份医嘱主要的不合理问题是用法用量不适宜、给药途径不适宜、适应证不适宜和重复给药;临床药师通过辅助用药点评、行政管理、信息手段等进行综合干预,每季度的辅助用药不合理率、用量前50名和前100名(按金额)药品中辅助用药的数目均呈下降趋势。结论临床药师通过干预辅助用药的医嘱审核,能提高辅助用药的安全性,降低不合理使用率。辅助用药的合理使用需要临床药师、行政管理部门和临床医师共同努力。
OBJECTIVE To promote the rational use of the adjuvant medicine. METHODS Main problems of special evaluation of the adjuvant medication in our hospital in 2015 were analyzed respectively. The effects of intervention were evaluated. RESULTS The drug which have many problems in medical order checking were Lentinan injection( 100. 00%),Sodium deoxyribonucleotide injection( 67. 50%) and Calf spleen extract injection( 60. 00%). Main problems include unsuitable dosage,unsuitable route of administration,unclear indication and repeated administration. Through comments on medical order by clinical pharmacist,administrative intervention and information intervention,the ratio of unreasonable medical order and the numbers of adjuvant medication in top 50 and100 showed a downward trend. CONCLUSION Clinical pharmacists can improve the safety and reduce the unrational use of adjuvant drug through comments on medical order. The rationality of adjuvant drug use is needed to work together by clinical pharmacists,administrative department and clinical doctors.

关键词(KeyWords)： 辅助用药;临床药师;干预
adjuvant medicine;clinical pharmacists;intervention

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 曹媛;邓蓉蓉;孙萍萍;
CAO Yuan;DENG Rongrong;SUN pingping;Pharmacy Departnent of The First Affiliated Hospital,Sun Yat-Sen University;

Email:

DOI:

参考文献(References)：

• [1]赖延锦.浅谈辅助用药在临床药物治疗中的价值[J].中国医药指南,2014,12(13):389-390.
• [2]韩爽,钟敏涛,李锦,等.我国辅助用药应用现状及管理对策初探[J].中国药学杂志,2016,51(8):678-682.
• [3]刘飞,单春燕,李娜.辅助用药临床应用管理的探讨[J].中国医院药学杂志,2016,36(17):394.
• [4]韩容,赵志刚.对医疗机构如何加强辅助用药管控的思考[J].药品评价,2016,13(4):21-25.
• [5]徐媛,徐蔚蔚,李扬.辅助用药临床应用情况分析[J].中国医院药学杂志,2017,37(1).73-75.
• [6]曾晓敏,司徒冰,黄娜,等.某三甲医院CCU辅助用药和中药注射剂用药情况调查[J].今日药学,2015,25(3):192-194.
• [7]王丽,蔡德芳,陈勇,等.辅助用药分类方法探索[J].中国药师,2015,18(12):2156-2159.
• [8]卢秀花,杜瑞超.临床药师在辅助治疗药物监管中的作用与实践[J].药品评价,2016,13(2):34-40.
• [9]贾立华,赵振满,贾娜娜,等.临床药师参与抗肿瘤辅助用药医嘱审核及干预效果分析[J].中国药房,2013,24(39):3739-3742.
• [10]谢沐风.从药品检验专业视角解读我国注射剂不良反应/事件频发现象[J].药品评价,2013,10(8):6.
• [11]张宏丽,许建辉,李新.超说明书用药的安全隐患[J].实用药物与临床,2015,18(9):1140-1142.
• [12]林高翔.本院门诊处方重复用药分析[J].今日药学,2012,22(2).119-121.
• [13]黄荣海,黎家宏,邝凯铭.医院处方重复用药情况调查分析[J].药学实践杂志,2008,26(1):55-56.
• [14]Reis W C,Scopel C T,Correr C J,et al.Analysis of clinical pharmacist interventions in a tertiary teaching hospital in Brazil[J].Einstein(Sao Paulo),2013,11(2):190.
• [15]林建昌.临床药学服务在癌症规范化治疗示范病房中的应用探讨[J].今日药学,2013,23(3):168-170.
• [16]梁宇.新形势下我院临床药师开展药学服务的工作模式探讨[J].山西医药杂志,2012,41(7):760-761.
• [17]钟运香,尹霖,刘燕,等.不合理处方事前干预分析与分诊断单元服务[J].广东药学院学报,2016,32(4):485-489.