1例带状疱疹合并AKI患者抗病毒及镇痛用药分析Analysis of Antiviral and Analgesic Drugs in a Patient with Herpes Zoster Complicated with AKI
刘晶;潘裕华;董伟;李锐钊;梁馨苓;劳海燕;
LIU Jing;PAN Yuhua;DONG Wei;LI Ruizhao;LIANG Xinling;LAO Haiyan;Department of Pharmacy,Zhujiang Hospital of Southern Medical University;Department of Pharmacy,Guangdong Provincial People's Hospital/Guangdong Academy of Medical Sciences;Department of Nephrology,Guangdong Provincial People's Hospital/Guangdong Academy of Medical Sciences;
摘要(Abstract):
目的探讨临床药师在带状疱疹合并急性肾损伤(acute kidney injury,AKI)患者临床治疗中发挥的作用。方法临床药师对1例狼疮肾炎合并带状疱疹与AKI患者的抗病毒和镇痛治疗方案进行分析,并进行药学监护。结果临床药师建议医生根据患者肾功能调整喷昔洛韦剂量。患者出现头晕、恶心不良反应时药师建议调整镇痛方案并对患者进行了详细的用药教育。结论药师参与临床治疗,有助于提高患者用药的安全性及有效性。
OBJECTIVE To explore the role of clinical pharmacists in the treatment of patients with herpes zoster and acute kidney injury( AKI). METHODS The clinical pharmacist analyzed the antiviral and analgesic drugs of a patient with lupus nephritis complicated with herpes zoster and AKI,and performed pharmacological care. RESULTS The clinical pharmacist suggested the doctor adjust the dose of penciclovir according to the patient's renal function. When the patient developed dizziness and nausea symptoms,the pharmacist suggested adjusting the analgesic drugs and provided detailed medication education for the patient. CONCLUSION The participation of pharmacists in clinical treatment can help improve the safety and effectiveness of medications for patients.
关键词(KeyWords):
带状疱疹;急性肾损伤;用药分析;药学监护
herpes zoster;acute kidney injury;analysis of the drug regimen;pharmaceutical care
基金项目(Foundation): 广东省医院药学研究基金(2018A24)
作者(Author):
刘晶;潘裕华;董伟;李锐钊;梁馨苓;劳海燕;
LIU Jing;PAN Yuhua;DONG Wei;LI Ruizhao;LIANG Xinling;LAO Haiyan;Department of Pharmacy,Zhujiang Hospital of Southern Medical University;Department of Pharmacy,Guangdong Provincial People's Hospital/Guangdong Academy of Medical Sciences;Department of Nephrology,Guangdong Provincial People's Hospital/Guangdong Academy of Medical Sciences;
Email:
DOI:
参考文献(References):
- [1]Werner R N,Nikkels A F,Marinovi B,et al.European consensusbased(S2k)Guideline on the Management of Herpes Zoster-guided by the European Dermatology Forum(EDF)in cooperation with the European Academy of Dermatology and Venereology(EADV),Part2:Treatment[J].Journal of the European Academy of Dermatology&Venereology Jeadv,2017,31(1):20-29.
- [2]Sauerbrei A.Diagnosis,antiviral therapy,and prophylaxis of varicellazoster virus infections[J].Eur J Clin Microbiol Infect Dis,2016,35(5):723-734.
- [3]关冰.狼疮性肾炎并发感染的临床研究概况[J].湖北中医杂志,2017,39(12):55-57.
- [4]杜晓兵.狼疮性肾炎并发医院感染的临床特点及预防[J].河北联合大学学报(医学版),2012,14(4):515-516.
- [5]黄灵,廉成翔,吴宁俊,等.狼疮性肾炎患者并发双侧带状疱疹1例[J].中国中西医结合皮肤性病学杂志,2015,14(1):54-55.
- [6]尹广,陈欣.急性肾损伤的定义及其临床诊断新标准[J].西部医学,2013,25(12):1916-1918.
- [7]王洪亮,刘瑞金,于凯江.急性肾损伤诊断标准的变迁如何影响其临床治疗[J].中华重症医学电子杂志,2017,3(1):5-8.
- [8]刘良裕,虞林玉.1例带状疱疹患者临床抗病毒治疗的药学监护[J].抗感染药学,2017,14(5):966-967,994.
- [9]操银针,熊丽娜.对1例带状疱疹并慢性肾功能不全患者的药学监护[J].中国医院药学杂志,2013,33(13):1096-1098.
- [10]中国医师协会皮肤科医师分会带状疱疹专家共识工作组.带状疱疹中国专家共识[J].中华皮肤科杂志,2018,51(6):403-408.
- [11]钟瑞平,王茹,赖菊英.喷昔洛韦治疗带状疱疹疗效观察[J].中国医学创新,2013,10(35):102-103.
- [12]相勇.喷昔洛韦治疗带状疱疹的临床疗效观察[J].中国医药指南,2015,13(32):107-108.
- [13]林静,董秀芹.注射用喷昔洛韦联合威伐光治疗带状疱疹的临床效果[J].中国医药导报,2016,13(13):122-124.
- [14]吉宁,赵行,曾昕,等.核苷类抗疱疹病毒药物的研究进展[J].国际口腔医学杂志,2018,45(3):351-357.
- [15]周梅生,王立明,傅尚希,等.注射用喷昔洛韦在预防肾移植患者病毒感染中的应用[J].中国医院药学杂志,2012,32(3):206-208.
- [16]费琳,胡征,吴丹丹,等.2种抗病毒药物预防肾移植术后巨细胞病毒肺炎的疗效及安全性探讨[J].中国抗生素杂志,2015,40(10):776-779.
- [17]带状疱疹后神经痛诊疗共识编写专家组.带状疱疹后神经痛诊疗中国专家共识[J].中国疼痛医学杂志,2016,22(3):161-167.
- [18]黄美媚,李国兴,钟剑萍,等.普瑞巴林治疗带状疱疹后神经痛54例疗效[J].包头医学院学报,2016,32(5):87-88.
- [19]奚奇,万成福,刘妍,等.普瑞巴林治疗糖尿病合并带状疱疹后神经痛的临床疗效观察[J].实用药物与临床,2017,20(7):816-818.
- [20]徐冬玲.带状疱疹后遗神经痛痛的护理方法探讨[J].实用临床护理学电子杂志,2017,2(50):103.
- [21]朱璇璇.带状疱疹急性期神经痛的疼痛管理及护理进展[J].全科护理,2018,16(36):4516-4519.
- 刘晶
- 潘裕华
- 董伟
- 李锐钊
- 梁馨苓
- 劳海燕
LIU Jing- PAN Yuhua
- DONG Wei
- LI Ruizhao
- LIANG Xinling
- LAO Haiyan
- Department of Pharmacy
- Zhujiang Hospital of Southern Medical University
- Department of Pharmacy
- Guangdong Provincial People's Hospital/Guangdong Academy of Medical Sciences
- Department of Nephrology
- Guangdong Provincial People's Hospital/Guangdong Academy of Medical Sciences
- 刘晶
- 潘裕华
- 董伟
- 李锐钊
- 梁馨苓
- 劳海燕
LIU Jing- PAN Yuhua
- DONG Wei
- LI Ruizhao
- LIANG Xinling
- LAO Haiyan
- Department of Pharmacy
- Zhujiang Hospital of Southern Medical University
- Department of Pharmacy
- Guangdong Provincial People's Hospital/Guangdong Academy of Medical Sciences
- Department of Nephrology
- Guangdong Provincial People's Hospital/Guangdong Academy of Medical Sciences